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What is hyperthyroidism?

Cats with hyperthyroidism have a thyroid gland that is producing excessive amounts of thyroid hormones. An overactive thyroid causes a dramatic increase in the body’s metabolic rate, leading to weight loss among other symptoms.

Hyperthyroidism, or ‘overactive thyroid’, occurs when the thyroid gland over-produces thyroid hormones. Your cat’s thyroid gland is located in its neck. It is divided into two parts (called lobes) which lie on either side of the windpipe (trachea).

When a cat has hyperthyroidism, either one or both of the thyroid lobes become enlarged (both lobes are affected in 70% of cases). This leads to excessive production of the thyroid hormones T4 (also known as thyroxine) and T3 (also known as triiodothyronine).

These hormones:

  • Are essential for proper growth of body cells and the development of these cells for specific roles in the body
  • Help regulate the metabolism of protein, fat and carbohydrate by cells
  • Are involved in the regulation of heat production and oxygen consumption and therefore a wide range of metabolic processes

As a result, an excess of thyroid hormones affects the function of virtually every organ system.

What causes hyperthyroidism?

The reasons for the change in the thyroid gland are not fully known.

In 98% of cases, the enlargement of the lobe(s) is benign and non-cancerous. In these cases, diagnosis and treatment are both straightforward and successful. In the remaining 2% of cases, the enlargement is due to a malignant cancerous growth of the thyroid gland.

Whatever the cause of the enlargement, the result is the same – more thyroid hormones are released.

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This site is provided as an information service for veterinary professionals and the owners of cats who have been prescribed Felimazole by their vet. Felimazole is a prescription-only medicine, available only from your veterinary surgeon. Any questions about your cat should be directed to your veterinary practice. Felimazole is a registered trademark of Dechra Limited.

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